4P0M

Crystal structure of an evolved putative penicillin-binding protein homolog, Rv2911, from Mycobacterium tuberculosis

Replaces:  2BCF

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	D-alanyl-D-alanine carboxypeptidase	polymer	276	29072.5	1	UniProt (Q7D6F2) Pfam (PF00768)	Mycobacterium tuberculosis	Probable penicillin-binding protein DacB2 (D-alanyl-D-alanine carboxypeptidase) (DD-peptidase) (DD-carboxypeptidase) (PBP) (DD-transpeptidase) (Serine-type D-ala-D-ala carboxypeptidase) (D-amino acid hydrolase)
2	B (A)	water	water		18.0	150	Chemie (HOH)

Sequence modifications

A: 25 - 291 (UniProt: Q7D6F2)

PDB	External Database	Details
Mse 24	-	initiating methionine
Val 113	Ala 113	engineered mutation
Ile 197	Thr 197	engineered mutation
Asp 208	Asn 208	engineered mutation
Asp 289	Gly 289	engineered mutation
Gly 292	-	expression tag
Ser 293	-	expression tag
His 294	-	expression tag
His 295	-	expression tag
His 296	-	expression tag
His 297	-	expression tag
His 298	-	expression tag
His 299	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	29072.5
All*	Total formula weight	29072.5

*Water molecules are not included.