4P0L

Crystal Structure of Double Loop-Swapped Interleukin-36Ra With Additional Point Mutations

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Interleukin-36 receptor antagonist/Interleukin-36 gamma chimera protein	polymer	154	16769.0	1	UniProt (Q9UBH0) UniProt (Q9NZH8) Pfam (PF00340)	Homo sapiens (Human)
2	B (A)	water	water		18.0	139	Chemie (HOH)

Sequence modifications

A: 2 - 49 (UniProt: Q9UBH0)

PDB	External Database	Details
Ser 2	Val 2	engineered mutation

A: 50 - 58 (UniProt: Q9NZH8)
A: 59 - 139 (UniProt: Q9UBH0)

PDB	External Database	Details
Ala 107	Arg 103	engineered mutation
Ala 109	Met 105	engineered mutation

A: 140 - 146 (UniProt: Q9NZH8)
A: 147 - 155 (UniProt: Q9UBH0)

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	16769.0
All*	Total formula weight	16769.0

*Water molecules are not included.