4OWQ

Anthranilate phosphoribosyl transferase from Mycobacterium tuberculosis in complex with 3-methylanthranilate, PRPP and Magnesium

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Anthranilate phosphoribosyltransferase	polymer	378	38848.9	2	UniProt (P66992) Pfam (PF02885) Pfam (PF00591) UniProt (by SIFTS) (P9WFX5)	Mycobacterium tuberculosis
2	C, D, I (A, B)	MAGNESIUM ION	non-polymer		24.3	3	Chemie (MG)
3	E, J (A, B)	1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose	non-polymer		390.1	2	Chemie (PRP)
4	F, K (A, B)	2-azanyl-3-methyl-benzoic acid	non-polymer		151.2	2	Chemie (3M0)
5	G, H (A)	GLYCEROL	non-polymer		92.1	2	Chemie (GOL)
6	L (B)	IMIDAZOLE	non-polymer		69.1	1	Chemie (IMD)
7	M, N (A, B)	water	water		18.0	510	Chemie (HOH)

Sequence modifications

A, B: 1 - 370 (UniProt: P66992)

PDB	External Database	Details
Leu 371	-	expression tag
Glu 372	-	expression tag
His 373	-	expression tag
His 374	-	expression tag
His 375	-	expression tag
His 376	-	expression tag
His 377	-	expression tag
His 378	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	77697.8
Non-Polymers*	Number of molecules	10
	Total formula weight	1408.7
All*	Total formula weight	79106.4

*Water molecules are not included.