4OUB
A 2.20 angstroms X-ray crystal structure of E268A 2-aminomucaonate 6-semialdehyde dehydrogenase catalytic intermediate from Pseudomonas fluorescens
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | 2-aminomuconate 6-semialdehyde dehydrogenase | polymer | 483 | 52062.6 | 4 | UniProt (Q83V33) Pfam (PF00171) | Pseudomonas fluorescens | |
| 2 | E, H, K, N (A, B, C, D) | NICOTINAMIDE-ADENINE-DINUCLEOTIDE | non-polymer | 663.4 | 4 | Chemie (NAD) | |||
| 3 | F, I, L, O (A, B, C, D) | SODIUM ION | non-polymer | 23.0 | 4 | Chemie (NA) | |||
| 4 | G, J, M, P (A, B, C, D) | (2Z,4E)-2-hydroxy-6-oxohexa-2,4-dienoic acid | non-polymer | 142.1 | 4 | Chemie (2VS) | |||
| 5 | Q, R, S, T (A, B, C, D) | water | water | 18.0 | 882 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 18 - 500 (UniProt: Q83V33)
| PDB | External Database | Details |
|---|---|---|
| Ala 268 | Glu 268 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 208250.2 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 3314.1 | |
| All* | Total formula weight | 211564.3 |
