4OTH
Crystal Structure of PRK1 Catalytic Domain in Complex with Ro-31-8220
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Serine/threonine-protein kinase N1 | polymer | 341 | 38341.5 | 1 | UniProt (Q16512) Pfam (PF00069) Pfam (PF00433) | Homo sapiens (human) | Protease-activated kinase 1, PAK-1, Protein kinase C-like 1, Protein kinase C-like PKN, Protein kinase PKN-alpha, Protein-kinase C-related kinase 1, Serine-threonine protein kinase N |
| 2 | B (A) | BISINDOLYLMALEIMIDE IX | non-polymer | 457.5 | 1 | Chemie (DRN) | |||
| 3 | C (A) | water | water | 18.0 | 302 | Chemie (HOH) |
Sequence modifications
A: 611 - 948 (UniProt: Q16512)
| PDB | External Database | Details |
|---|---|---|
| Gly 608 | - | expression tag |
| Ser 609 | - | expression tag |
| Met 610 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 38341.5 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 457.5 | |
| All* | Total formula weight | 38799.1 |
