4OTG
Crystal Structure of PRK1 Catalytic Domain in Complex with Lestaurtinib
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Serine/threonine-protein kinase N1 | polymer | 341 | 38341.5 | 1 | UniProt (Q16512) Pfam (PF00069) Pfam (PF00433) | Homo sapiens (human) | Protease-activated kinase 1, PAK-1, Protein kinase C-like 1, Protein kinase C-like PKN, Protein kinase PKN-alpha, Protein-kinase C-related kinase 1, Serine-threonine protein kinase N |
| 2 | B (A) | Lestaurtinib | non-polymer | 439.5 | 1 | Chemie (2V9) PubChem (126565) PubChem (56846346) PubChem (59476505) PubChem (59922033) PubChem (70810196) PubChem (71717270) PubChem (73952981) PubChem (98405361) PubChem (9867822) PubChem (9867823) PubChem (9932888) PubChem (11419279) PubChem (14096316) PubChem (14096317) PubChem (172873885) | |||
| 3 | C (A) | water | water | 18.0 | 5 | Chemie (HOH) |
Sequence modifications
A: 611 - 948 (UniProt: Q16512)
| PDB | External Database | Details |
|---|---|---|
| Gly 608 | - | expression tag |
| Ser 609 | - | expression tag |
| Met 610 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 38341.5 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 439.5 | |
| All* | Total formula weight | 38781.0 |
