4ORB
Crystal structure of mouse calcineurin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform | polymer | 519 | 58754.7 | 1 | UniProt (P63328) Pfam (PF00149) | Mus musculus (mouse) | CAM-PRP catalytic subunit, Calmodulin-dependent calcineurin A subunit alpha isoform |
| 2 | B (B) | Calcineurin subunit B type 1 | polymer | 170 | 19322.9 | 1 | UniProt (Q63810) Pfam (PF13499) | Mus musculus (mouse) | Protein phosphatase 2B regulatory subunit 1, Protein phosphatase 3 regulatory subunit B alpha isoform 1 |
| 3 | C (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 4 | D (A) | FE (III) ION | non-polymer | 55.8 | 1 | Chemie (FE) | |||
| 5 | E, F, G, H (B) | CALCIUM ION | non-polymer | 40.1 | 4 | Chemie (CA) | |||
| 6 | I, J (A, B) | water | water | 18.0 | 15 | Chemie (HOH) |
Sequence modifications
A: 1 - 511 (UniProt: P63328)
| PDB | External Database | Details |
|---|---|---|
| - | Ala 447 | SEE REMARK 999 |
| - | Thr 448 | SEE REMARK 999 |
| - | Val 449 | SEE REMARK 999 |
| - | Glu 450 | SEE REMARK 999 |
| - | Ala 451 | SEE REMARK 999 |
| - | Ile 452 | SEE REMARK 999 |
| - | Glu 453 | SEE REMARK 999 |
| - | Ala 454 | SEE REMARK 999 |
| - | Asp 455 | SEE REMARK 999 |
| - | Glu 456 | SEE REMARK 999 |
| Leu 512 | - | expression tag |
| Glu 513 | - | expression tag |
| His 514 | - | expression tag |
| His 515 | - | expression tag |
| His 516 | - | expression tag |
| His 517 | - | expression tag |
| His 518 | - | expression tag |
| His 519 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 78077.6 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 281.6 | |
| All* | Total formula weight | 78359.2 |
