4OLW
Crystal structure of antibody VRC07-G54H in complex with clade A/E 93TH057 HIV-1 gp120 core
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (G) | Envelope glycoprotein gp160 | polymer | 353 | 39211.4 | 1 | UniProt (Q0ED31) Pfam (PF00516) | Human immunodeficiency virus 1 | |
| 2 | B (H) | Antigen binding fragment of heavy chain: Antibody VRC01 | polymer | 228 | 25005.3 | 1 | Homo sapiens | ||
| 3 | C (L) | Antigen binding fragment of light chain: Antibody VRC01 | polymer | 210 | 23159.7 | 1 | Homo sapiens | ||
| 4 | D, E, F, G, H... (G) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 10 | Chemie (NAG) | |||
| 5 | N, O, P (G, H, L) | water | water | 18.0 | 25 | Chemie (HOH) |
Sequence modifications
G: 44 - 123 (UniProt: Q0ED31)
G: 199 - 301 (UniProt: Q0ED31)
G: 324 - 492 (UniProt: Q0ED31)
G: 199 - 301 (UniProt: Q0ED31)
| PDB | External Database | Details |
|---|---|---|
| Gly 124 | - | linker |
| Gly 198 | - | linker |
| PDB | External Database | Details |
|---|---|---|
| Gly 318 | - | linker |
| Gly 319 | - | linker |
| Ser 320 | - | linker |
| Gly 321 | - | linker |
| Ser 322 | - | linker |
| Gly 323 | - | linker |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 87376.4 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 2212.1 | |
| All* | Total formula weight | 89588.5 |
