4OLV

Crystal structure of antibody VRC07-G54F in complex with clade A/E 93TH057 HIV-1 gp120 core

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (G)	Envelope glycoprotein gp160	polymer	353	39211.4	1	UniProt (Q0ED31) Pfam (PF00516)	Human immunodeficiency virus 1
2	B (H)	Antigen binding fragment of heavy chain: Antibody VRC01	polymer	228	25014.3	1		Homo sapiens
3	C (L)	Antigen binding fragment of light chain: Antibody VRC01	polymer	210	23089.6	1		Homo sapiens
4	D, E, F, G, H... (G)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	11	Chemie (NAG)
5	O, P, Q (G, H, L)	water	water		18.0	294	Chemie (HOH)

Sequence modifications

G: 44 - 123 (UniProt: Q0ED31)
G: 199 - 301 (UniProt: Q0ED31)

PDB	External Database	Details
Gly 124	-	linker
Gly 198	-	linker

G: 324 - 492 (UniProt: Q0ED31)

PDB	External Database	Details
Gly 318	-	linker
Gly 319	-	linker
Ser 320	-	linker
Gly 321	-	linker
Ser 322	-	linker
Gly 323	-	linker

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	87315.4
Non-Polymers*	Number of molecules	11
	Total formula weight	2433.3
All*	Total formula weight	89748.6

*Water molecules are not included.