4OL0
Crystal structure of transportin-SR2, a karyopherin involved in human disease, in complex with Ran
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | GTP-binding nuclear protein Ran | polymer | 216 | 24456.1 | 1 | UniProt (P62826) Pfam (PF00071) | Homo sapiens (human) | Androgen receptor-associated protein 24, GTPase Ran, Ras-like protein TC4, Ras-related nuclear protein |
| 2 | B (B) | Transportin-3 | polymer | 921 | 104052.9 | 1 | UniProt (Q9Y5L0) Pfam (PF08389) | Homo sapiens (human) | Importin-12, Imp12, Transportin-SR, TRN-SR |
| 3 | C (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 4 | D (A) | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 1 | Chemie (GTP) | |||
| 5 | E, F (A, B) | water | water | 18.0 | 33 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 128509.0 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 547.5 | |
| All* | Total formula weight | 129056.5 |
