4OK1
Crystal structure of W741L-AR-LBD bound with co-regulator peptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Androgen receptor | polymer | 250 | 29015.0 | 1 | UniProt (P10275) Pfam (PF00104) | Homo sapiens (human) | Dihydrotestosterone receptor, Nuclear receptor subfamily 3 group C member 4 |
| 2 | B (B) | co-regulator peptide | polymer | 11 | 1267.4 | 1 | |||
| 3 | C (A) | R-BICALUTAMIDE | non-polymer | 430.4 | 1 | Chemie (198) | |||
| 4 | D, E (A, B) | water | water | 18.0 | 36 | Chemie (HOH) |
Sequence modifications
A: 670 - 919 (UniProt: P10275)
| PDB | External Database | Details |
|---|---|---|
| Leu 741 | Trp 741 | engineered mutation |
| Ala 760 | Arg 760 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 30282.4 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 430.4 | |
| All* | Total formula weight | 30712.8 |
