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4OI7

RAGE recognizes nucleic acids and promotes inflammatory responses to DNA

Replaces:  3S58
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Advanced glycosylation end product-specific receptorpolymer22324195.62UniProt (Q15109)
Pfam (PF08205)
Homo sapiens (human)RAGE, Receptor for advanced glycosylation end products
2C
(E)
5'-D(*CP*TP*GP*CP*AP*AP*CP*GP*AP*TP*GP*CP*TP*AP*CP*GP*AP*AP*CP*GP*TP*G)-3'polymer226761.41
3D
(F)
5'-D(*CP*AP*CP*GP*TP*TP*CP*GP*TP*AP*GP*CP*AP*TP*CP*GP*TP*TP*GP*CP*AP*G)-3'polymer226743.41
4E, F, G, H
(A, B)
1,2-ETHANEDIOLnon-polymer62.14Chemie (EDO)
5I, J
(A, B)
waterwater18.042Chemie (HOH)
Sequence modifications
A, B: 23 - 237 (UniProt: Q15109)
PDBExternal DatabaseDetails
Gly 19-expression tag
Ser 20-expression tag
Val 21-expression tag
Asp 22-expression tag
Ala 238-expression tag
Ala 239-expression tag
Ala 240-expression tag
Ser 241-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight61895.9
Non-Polymers*Number of molecules4
Total formula weight248.3
All*Total formula weight62144.2
*Water molecules are not included.

246031

PDB entries from 2025-12-10

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