4OHA
Crystal structure of T877A-AR-LBD bound with co-regulator peptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Androgen receptor | polymer | 250 | 29058.1 | 1 | UniProt (P10275) Pfam (PF00104) | Homo sapiens (human) | Dihydrotestosterone receptor, Nuclear receptor subfamily 3 group C member 4 |
| 2 | B (B) | co-regulator peptide | polymer | 12 | 1391.5 | 1 | |||
| 3 | C (A) | HYDROXYFLUTAMIDE | non-polymer | 292.2 | 1 | Chemie (HFT) | |||
| 4 | D (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 5 | E (A) | water | water | 18.0 | 280 | Chemie (HOH) |
Sequence modifications
A: 670 - 919 (UniProt: P10275)
| PDB | External Database | Details |
|---|---|---|
| Ala 760 | Arg 760 | engineered mutation |
| Ala 877 | Thr 877 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 30449.5 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 388.3 | |
| All* | Total formula weight | 30837.8 |
