4OGV
Co-Crystal Structure of MDM2 with Inhibitor Compound 49
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C | E3 ubiquitin-protein ligase Mdm2 | polymer | 95 | 11099.0 | 3 | UniProt (Q00987) Pfam (PF02201) In PDB | Homo sapiens (human) | Double minute 2 protein, Hdm2, Oncoprotein Mdm2, p53-binding protein Mdm2 |
| 2 | A, B, C | [(2S,5R,6R)-4-[(2S)-1-(tert-butylsulfonyl)butan-2-yl]-6-(3-chlorophenyl)-5-(4-chlorophenyl)-3-oxomorpholin-2-yl]acetic acid | non-polymer | 556.5 | 3 | Chemie (2U7) | |||
| 3 | water | water | 18.0 | 32 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 33297.0 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 1669.5 | |
| All* | Total formula weight | 34966.5 |
