4OFU
Crystal structure of AR-LBD bound with co-regulator peptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Androgen receptor | polymer | 250 | 29088.1 | 1 | UniProt (P10275) Pfam (PF00104) | Homo sapiens (human) | Dihydrotestosterone receptor, Nuclear receptor subfamily 3 group C member 4 |
| 2 | B (B) | co-regulator peptide | polymer | 12 | 1441.5 | 1 | synthetic construct | ||
| 3 | C (A) | 5-ALPHA-DIHYDROTESTOSTERONE | non-polymer | 290.4 | 1 | Chemie (DHT) PubChem (16395945) PubChem (1779160) PubChem (15) PubChem (23729584) PubChem (10635) PubChem (44264584) PubChem (44307156) PubChem (44308180) PubChem (44314545) PubChem (147320) PubChem (1779165) PubChem (54132599) PubChem (1779163) PubChem (44403751) PubChem (67080676) PubChem (68213431) PubChem (70627790) PubChem (57253355) PubChem (667503) PubChem (76333143) PubChem (2748143) PubChem (928651) PubChem (11302) PubChem (90350225) PubChem (968803) PubChem (6951009) PubChem (124916763) PubChem (6432518) PubChem (133612463) PubChem (7052570) PubChem (7052571) PubChem (11869360) PubChem (9965809) PubChem (10379482) PubChem (10902374) PubChem (124305346) PubChem (124335861) PubChem (124350819) PubChem (124362930) PubChem (124402106) PubChem (124420348) PubChem (11860392) PubChem (11867857) PubChem (11867858) PubChem (11867859) PubChem (11867860) PubChem (11869358) PubChem (11869359) PubChem (11869361) PubChem (11914201) PubChem (11920866) PubChem (12446746) PubChem (12446747) PubChem (12446748) PubChem (12446749) PubChem (12446752) PubChem (124907326) PubChem (124907327) PubChem (16111632) PubChem (134753818) PubChem (139564330) PubChem (141909893) PubChem (142776876) PubChem (145087815) PubChem (156740897) PubChem (162854571) PubChem (162854572) PubChem (162854573) PubChem (164663566) PubChem (165146196) PubChem (165431280) | |||
| 4 | D, E (A, B) | water | water | 18.0 | 57 | Chemie (HOH) |
Sequence modifications
A: 670 - 919 (UniProt: P10275)
| PDB | External Database | Details |
|---|---|---|
| Ala 760 | Arg 760 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 30529.6 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 290.4 | |
| All* | Total formula weight | 30820.0 |
