4OEF
Crystal Structure Analysis of FGF2-Disaccharide (S6I2) complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Fibroblast growth factor 2 | polymer | 155 | 17249.7 | 1 | UniProt (P09038) Pfam (PF00167) | Homo sapiens (human) | FGF-2, Basic fibroblast growth factor, bFGF, Heparin-binding growth factor 2, HBGF-2 |
| 2 | B (B) | 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-1-O-methyl-2-O-sulfo-alpha-L-idopyranuronic acid | branched | 609.5 | 1 | In PDB GlyTouCan (G68165WJ) | |||
| 3 | C (A) | water | water | 18.0 | 95 | Chemie (HOH) |
Sequence modifications
A: -8 - 146 (UniProt: P09038)
| PDB | External Database | Details |
|---|---|---|
| Ser 69 | Cys 211 | engineered mutation |
| Ser 87 | Cys 229 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 17249.7 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 609.5 | |
| All* | Total formula weight | 17859.2 |
