4ODF
Co-Crystal Structure of MDM2 with Inhibitor Compound 47
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | E3 ubiquitin-protein ligase Mdm2 | polymer | 105 | 12045.1 | 1 | UniProt (Q00987) Pfam (PF02201) | Homo sapiens (human) | Double minute 2 protein, Hdm2, Oncoprotein Mdm2, p53-binding protein Mdm2 |
| 2 | B (A) | 6-{[(2S,5R,6R)-4-[(1S)-2-(tert-butylsulfonyl)-1-cyclopropylethyl]-6-(3-chlorophenyl)-5-(4-chlorophenyl)-2-methyl-3-oxomorpholin-2-yl]methyl}pyridine-3-carboxylic acid | non-polymer | 659.6 | 1 | Chemie (2U1) | |||
| 3 | C (A) | water | water | 18.0 | 4 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 12045.1 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 659.6 | |
| All* | Total formula weight | 12704.7 |
