4OBZ

Structure of Cathepsin D with inhibitor 2-(3,4-dimethoxyphenyl)-N-[N-(4-methylbenzyl)carbamimidoyl]acetamide

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C	Cathepsin D light chain	polymer	103	11273.6	2	UniProt (P07339) In PDB	Homo sapiens (human)
2	B, D	Cathepsin D heavy chain	polymer	243	26540.6	2	UniProt (P07339) Pfam (PF00026) In PDB	Homo sapiens (human)
3	E	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	1	In PDB GlyTouCan (G42666HT)
4	A	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	1	Chemie (NAG)
5	B	2-(3,4-dimethoxyphenyl)-N-[N-(4-methylbenzyl)carbamimidoyl]acetamide	non-polymer		341.4	1	Chemie (2S4)
6		water	water		18.0	38	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	75628.2
Branched	Number of molecules	1
	Total formula weight	424.4
Non-Polymers*	Number of molecules	2
	Total formula weight	562.6
All*	Total formula weight	76615.3

*Water molecules are not included.