4OBS
Crystal structure of human alpha-L-iduronidase in the P212121 form
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Alpha-L-iduronidase | polymer | 627 | 70053.3 | 1 | UniProt (P35475) Pfam (PF01229) Pfam (PF21200) In PDB | Homo sapiens (human) | |
| 2 | B | alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1073.0 | 1 | In PDB GlyTouCan (G56014GC) | |||
| 3 | A | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
| 4 | A | GLYCEROL | non-polymer | 92.1 | 6 | Chemie (GOL) | |||
| 5 | A | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 6 | A | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 7 | water | water | 18.0 | 143 | Chemie (HOH) |
Sequence modifications
A: 27 - 653 (UniProt: P35475)
| PDB | External Database | Details |
|---|---|---|
| Gln 33 | His 33 | SEE REMARK 999 |
| Pro 63 | Gln 63 | SEE REMARK 999 |
| Gln 105 | Arg 105 | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 70053.3 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 1073.0 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 1126.5 | |
| All* | Total formula weight | 72252.8 |
