4O8L

Structure of sortase A from Streptococcus pneumoniae

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C, D (A, C, D)	Sortase	polymer	187	21109.8	3	UniProt (Q8DPM3) Pfam (PF04203)	Streptococcus pneumoniae
2	B (B)	Sortase	polymer	187	21125.8	1	UniProt (Q8DPM3) Pfam (PF04203)	Streptococcus pneumoniae
3	E, F, G, H (A, B, C, D)	water	water		18.0	54	Chemie (HOH)

Sequence modifications

A, C, D: 82 - 247 (UniProt: Q8DPM3)

PDB	External Database	Details
Met 61	-	expression tag
Gly 62	-	expression tag
Ser 63	-	expression tag
Ser 64	-	expression tag
His 65	-	expression tag
His 66	-	expression tag
His 67	-	expression tag
His 68	-	expression tag
His 69	-	expression tag
His 70	-	expression tag
Ser 71	-	expression tag
Ser 72	-	expression tag
Gly 73	-	expression tag
Leu 74	-	expression tag
Val 75	-	expression tag
Pro 76	-	expression tag
Arg 77	-	expression tag
Gly 78	-	expression tag
Ser 79	-	expression tag
His 80	-	expression tag
Met 81	-	expression tag
Ala 176	Thr 176	engineered mutation

B: 82 - 247 (UniProt: Q8DPM3)

PDB	External Database	Details
Met 61	-	expression tag
Gly 62	-	expression tag
Ser 63	-	expression tag
Ser 64	-	expression tag
His 65	-	expression tag
His 66	-	expression tag
His 67	-	expression tag
His 68	-	expression tag
His 69	-	expression tag
His 70	-	expression tag
Ser 71	-	expression tag
Ser 72	-	expression tag
Gly 73	-	expression tag
Leu 74	-	expression tag
Val 75	-	expression tag
Pro 76	-	expression tag
Arg 77	-	expression tag
Gly 78	-	expression tag
Ser 79	-	expression tag
His 80	-	expression tag
Met 81	-	expression tag
Ala 176	Thr 176	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	84455.4
All*	Total formula weight	84455.4

*Water molecules are not included.