4O7U
Etherocomplex of Enteroccocus faecalis thymidylate synthase with 5-hydroxymethilene-6-hydrofolic acid and the phtalimidic inhibitor SS7
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D | Thymidylate synthase | polymer | 315 | 36386.0 | 4 | UniProt (Q834R3) Pfam (PF00303) In PDB | Enterococcus faecalis | TS, TSase |
| 2 | A, C, D | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
| 3 | B | 5-HYDROXYMETHYLENE-6-HYDROFOLIC ACID | non-polymer | 473.4 | 1 | Chemie (THF) | |||
| 4 | C, D | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
| 5 | D | 4-{[(2S)-2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)propyl]oxy}-3,5-dimethylphenyl acetate | non-polymer | 367.4 | 1 | Chemie (SS7) | |||
| 6 | water | water | 18.0 | 205 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 145543.9 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1349.2 | |
| All* | Total formula weight | 146893.1 |
