4O6A
Mouse cyclic GMP-AMP synthase (cGAS) in complex with DNA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D (A, B) | Cyclic GMP-AMP synthase | polymer | 362 | 42556.2 | 2 | UniProt (Q8C6L5) Pfam (PF03281) Pfam (PF20266) | Mus musculus (mouse) | cGAMP synthase, cGAS, m-cGAS, Mab-21 domain-containing protein 1 |
| 2 | B, E (D, C) | DNA1 | polymer | 17 | 5253.5 | 2 | |||
| 3 | C, F (E, F) | DNA2 | polymer | 17 | 5159.3 | 2 | |||
| 4 | G, H (A, B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 5 | I, J, K, L, M... (A, D, E, B, C...) | water | water | 18.0 | 1049 | Chemie (HOH) |
Sequence modifications
A, B: 147 - 507 (UniProt: Q8C6L5)
| PDB | External Database | Details |
|---|---|---|
| Met 146 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 105938.1 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 130.8 | |
| All* | Total formula weight | 106068.9 |
