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4O69

Human cyclic GMP-AMP synthase (cGAS) in complex with sulfate ion

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Cyclic GMP-AMP synthasepolymer36342536.11UniProt (Q8N884)
Pfam (PF03281)
Pfam (PF20266)
Homo sapiens (human)cGAMP synthase, cGAS, h-cGAS, Mab-21 domain-containing protein 1
2B
(A)
ZINC IONnon-polymer65.41Chemie (ZN)
3C, D, E
(A)
SULFATE IONnon-polymer96.13Chemie (SO4)
4F
(A)
waterwater18.0169Chemie (HOH)
Sequence modifications
A: 161 - 522 (UniProt: Q8N884)
PDBExternal DatabaseDetails
Met 160-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight42536.1
Non-Polymers*Number of molecules4
Total formula weight353.6
All*Total formula weight42889.7
*Water molecules are not included.

247536

PDB entries from 2026-01-14

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