4O5L

Crystal structure of broadly neutralizing antibody F045-092

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (L)	Fab F045-092 light chain	polymer	230	24108.4	1	UniProt (P0DOY3) Pfam (PF07654)	Homo sapiens (human)	Ig lambda chain C region DOT,Ig lambda chain C region NEWM,Ig lambda-3 chain C regions
2	B (H)	Fab F045-092 heavy chain	polymer	240	25691.7	1	UniProt (A8K008) Pfam (PF07686) Pfam (PF07654)	Homo sapiens (human)
3	C (L)	PHOSPHATE ION	non-polymer		95.0	1	Chemie (PO4)
4	D, E (L, H)	water	water		18.0	457	Chemie (HOH)

Sequence modifications

L: 1 - 107 (PDB: 4O5L)
L: 108 - 212 (UniProt: P0DOY3)

PDB	External Database	Details
Ala 213	-	expression tag
Arg 214	-	expression tag
Leu 215	-	expression tag
Gly 216	-	expression tag
Gly 217	-	expression tag
Gly 218	-	expression tag
Asp 219	-	expression tag
Tyr 220	-	expression tag
Lys 221	-	expression tag
Asp 222	-	expression tag
Asp 223	-	expression tag
Asp 224	-	expression tag
Asp 225	-	expression tag
Lys 226	-	expression tag

H: 1 - 100 (PDB: 4O5L)
H: 101 - 216 (UniProt: A8K008)

PDB	External Database	Details
His 217	-	expression tag
His 218	-	expression tag
His 219	-	expression tag
His 220	-	expression tag
His 221	-	expression tag
His 222	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	49800.2
Non-Polymers*	Number of molecules	1
	Total formula weight	95.0
All*	Total formula weight	49895.1

*Water molecules are not included.