4O5F

Crystal structure of Type III pantothenate kinase from Burkholderia thailandensis in complex with pantothenate and phosphate

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Type III pantothenate kinase	polymer	280	29324.3	2	UniProt (Q2T1M2) Pfam (PF03309)	Burkholderia thailandensis	PanK-III, Pantothenic acid kinase
2	C, L (A, B)	PANTOTHENOIC ACID	non-polymer		219.2	2	Chemie (PAU)
3	D, M (A, B)	PHOSPHATE ION	non-polymer		95.0	2	Chemie (PO4)
4	E, N (A, B)	ADENOSINE-5'-TRIPHOSPHATE	non-polymer		507.2	2	Chemie (ATP)
5	F, G (A)	CHLORIDE ION	non-polymer		35.5	2	Chemie (CL)
6	H, I, O (A, B)	GLYCEROL	non-polymer		92.1	3	Chemie (GOL)
7	J, K (A, B)	POTASSIUM ION	non-polymer		39.1	2	Chemie (K)
8	P, Q (A, B)	water	water		18.0	511	Chemie (HOH)

Sequence modifications

A, B: 1 - 259 (UniProt: Q2T1M2)

PDB	External Database	Details
Met -20	-	expression tag
Ala -19	-	expression tag
His -18	-	expression tag
His -17	-	expression tag
His -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
Met -12	-	expression tag
Gly -11	-	expression tag
Thr -10	-	expression tag
Leu -9	-	expression tag
Glu -8	-	expression tag
Ala -7	-	expression tag
Gln -6	-	expression tag
Thr -5	-	expression tag
Gln -4	-	expression tag
Gly -3	-	expression tag
Pro -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	58648.6
Non-Polymers*	Number of molecules	13
	Total formula weight	2068.2
All*	Total formula weight	60716.7

*Water molecules are not included.