4O5E
Structure of human DNA polymerase complexed with N7MG in the template base paired with incoming non-hydrolyzable TTP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | DNA polymerase beta | polymer | 329 | 37536.8 | 1 | UniProt (P06746) Pfam (PF14716) Pfam (PF10391) Pfam (PF14792) Pfam (PF14791) | Homo sapiens (human) | |
| 2 | B (T) | DNA (5'-D(*CP*CP*GP*AP*CP*(FMG)P*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3') | polymer | 16 | 4877.2 | 1 | synthetic construct | ||
| 3 | C (P) | DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3') | polymer | 10 | 3085.0 | 1 | synthetic construct | ||
| 4 | D (D) | DNA (5'-D(P*GP*TP*CP*GP*G)-3') | polymer | 5 | 1536.0 | 1 | synthetic construct | ||
| 5 | E (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 6 | F, G (A) | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) | |||
| 7 | H (A) | 5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]thymidine | non-polymer | 481.2 | 1 | Chemie (1FZ) | |||
| 8 | I, J, K, L (A, T, P, D) | water | water | 18.0 | 71 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 47035.0 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 551.5 | |
| All* | Total formula weight | 47586.5 |
