4O37

seminsynthetic RNase S1-15-3Pl-7/11

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Ribonuclease pancreatic, S-peptide	polymer	15	1773.9	1	UniProt (P61823) In PDB	Bos taurus	RNase 1, RNase A
2	B	Ribonuclease pancreatic, S-protein	polymer	104	11556.0	1	UniProt (P61823) Pfam (PF00074) In PDB	Bos taurus (bovine cow domestic cattle domestic cow)	RNase 1, RNase A
3	A	CHLORIDE ION	non-polymer		35.5	1	Chemie (CL)
4	B	SULFATE ION	non-polymer		96.1	2	Chemie (SO4)
5		water	water		18.0	139	Chemie (HOH)

Sequence modifications

A: 1 - 15 (UniProt: P61823)

PDB	External Database	Details
1mh 7	Lys 33	engineered mutation
1mh 11	Gln 37	engineered mutation
Nle 13	Met 39	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	13329.9
Non-Polymers*	Number of molecules	3
	Total formula weight	227.6
All*	Total formula weight	13557.5

*Water molecules are not included.