4O21
Product complex of metal-free PKAc, ATP-gamma-S and SP20.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | cAMP-dependent protein kinase catalytic subunit alpha | polymer | 342 | 40234.8 | 1 | UniProt (P05132) Pfam (PF00069) | Mus musculus (mouse) | PKA C-alpha |
| 2 | B (S) | Thio-phosphorylated peptide pSP20 | polymer | 20 | 2295.4 | 1 | UniProt (P61925) | Homo sapiens (human) | PKI-alpha, cAMP-dependent protein kinase inhibitor alpha, cAMP-dependent protein kinase inhibitor, muscle/brain isoform |
| 3 | C (A) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 1 | Chemie (ADP) | |||
| 4 | D, E (A, S) | water | water | 18.0 | 421 | Chemie (HOH) |
Sequence modifications
A: 15 - 350 (UniProt: P05132)
S: 501 - 520 (UniProt: P61925)
| PDB | External Database | Details |
|---|---|---|
| His 9 | - | expression tag |
| His 10 | - | expression tag |
| His 11 | - | expression tag |
| His 12 | - | expression tag |
| His 13 | - | expression tag |
| His 14 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Ala 516 | Asn 21 | engineered mutation |
| 2rx 517 | Ala 22 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 42530.2 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 427.2 | |
| All* | Total formula weight | 42957.4 |
