4NZL

Extracellular proteins of Staphylococcus aureus inhibit the neutrophil serine proteases

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Neutrophil elastase	polymer	218	23319.0	1	UniProt (P08246) Pfam (PF00089) In PDB	Homo sapiens (human)	Bone marrow serine protease, Elastase-2, Human leukocyte elastase, HLE, Medullasin, PMN elastase
2	B	Uncharacterized protein	polymer	114	12722.3	1	UniProt (Q99S64) Pfam (PF03642) UniProt (by SIFTS) (A0A0H3K0M1) In PDB	Staphylococcus aureus subsp. aureus
3	C, D	beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose	branched		732.7	2	In PDB GlyTouCan (G86566TX)
4		water	water		18.0	291	Chemie (HOH)

Sequence modifications

B: 43 - 141 (UniProt: Q99S64)

PDB	External Database	Details
Gly 28	-	expression tag
Ser 29	-	expression tag
Thr 30	-	expression tag
Asp 31	-	expression tag
Ser 32	-	expression tag
Asn 33	-	expression tag
Asn 34	-	expression tag
Gly 35	-	expression tag
Tyr 36	-	expression tag
Lys 37	-	expression tag
Glu 38	-	expression tag
Leu 39	-	expression tag
Thr 40	-	expression tag
Met 41	-	expression tag
Asp 42	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	36041.3
Branched	Number of molecules	2
	Total formula weight	1465.4
All*	Total formula weight	37506.6

*Water molecules are not included.