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4NY8

DNA polymerase beta with O6mG in the template base opposite to incoming non-hydrolyzable CTP with manganese in the active site

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
DNA polymerase betapolymer32637182.41UniProt (P06746)
Pfam (PF14716)
Pfam (PF10391)
Pfam (PF14792)
Pfam (PF14791)
Homo sapiens (human)
2B
(T)
5'-D(*CP*CP*GP*AP*CP*(6OG)P*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'polymer164858.21
3C
(P)
5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3'polymer103085.01
4D
(D)
5'-D(P*GP*TP*CP*GP*G)-3'polymer51536.01
5E, F
(A)
MANGANESE (II) IONnon-polymer54.92Chemie (MN)
6G, H
(A)
SODIUM IONnon-polymer23.02Chemie (NA)
7I
(A)
2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidinenon-polymer466.21Chemie (0KX)
8J, K, L, M
(A, T, P, D)
waterwater18.0120Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight46661.6
Non-Polymers*Number of molecules5
Total formula weight622.0
All*Total formula weight47283.7
*Water molecules are not included.

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PDB entries from 2025-06-11

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