4NW2

Tandem chromodomains of human CHD1 in complex with Influenza virus NS1 C-terminal tail trimethylated at K229

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C	Chromodomain-helicase-DNA-binding protein 1	polymer	194	22942.4	2	UniProt (O14646) Pfam (PF00385) In PDB	Homo sapiens (human)	CHD-1, ATP-dependent helicase CHD1
2	B, D	Nonstructural protein 1	polymer	15	1834.3	2	UniProt (T2F8K6) UniProt (by SIFTS) (P03495) In PDB	Influenza A virus
3	C, A, D	UNKNOWN ATOM OR ION	non-polymer			31	Chemie (UNX)
4	C, B	GLYCEROL	non-polymer		92.1	2	Chemie (GOL)
5		water	water		18.0	161	Chemie (HOH)

Sequence modifications

A, C: 268 - 443 (UniProt: O14646)

PDB	External Database	Details
Met 250	-	expression tag
His 251	-	expression tag
His 252	-	expression tag
His 253	-	expression tag
His 254	-	expression tag
His 255	-	expression tag
His 256	-	expression tag
Ser 257	-	expression tag
Ser 258	-	expression tag
Gly 259	-	expression tag
Arg 260	-	expression tag
Glu 261	-	expression tag
Asn 262	-	expression tag
Leu 263	-	expression tag
Tyr 264	-	expression tag
Phe 265	-	expression tag
Gln 266	-	expression tag
Gly 267	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	49553.4
Non-Polymers*	Number of molecules	33
	Total formula weight	184.2
All*	Total formula weight	49737.6

*Water molecules are not included.