4NSV
Lysobacter enzymogenes lysc endoproteinase K30R mutant covalently inhibited by TLCK
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Lysyl endopeptidase | polymer | 275 | 28749.2 | 2 | UniProt (Q7M135) Pfam (PF13365) | Lysobacter enzymogenes | Lys-C |
| 2 | C, F (A, B) | N-[(2S,3S)-7-amino-1-chloro-2-hydroxyheptan-3-yl]-4-methylbenzenesulfonamide (Bound Form) | non-polymer | 334.9 | 2 | BIRD (PRD_001217) Chemie (2OY) | |||
| 3 | D, G, H (A, B) | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 4 | E (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 5 | I, J (A, B) | water | water | 18.0 | 937 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 266 (UniProt: Q7M135)
| PDB | External Database | Details |
|---|---|---|
| Arg 30 | Lys 30 | engineered mutation |
| Gly 267 | - | expression tag |
| Ser 268 | - | expression tag |
| Gly 269 | - | expression tag |
| His 270 | - | expression tag |
| His 271 | - | expression tag |
| His 272 | - | expression tag |
| His 273 | - | expression tag |
| His 274 | - | expression tag |
| His 275 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 57498.4 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 993.4 | |
| All* | Total formula weight | 58491.8 |
