4NRQ
Crystal structure of human ALKBH5 in complex with pyridine-2,4-dicarboxylate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | RNA demethylase ALKBH5 | polymer | 230 | 26385.1 | 1 | UniProt (Q6P6C2) Pfam (PF13532) In PDB | Homo sapiens | Alkylated DNA repair protein alkB homolog 5, Alpha-ketoglutarate-dependent dioxygenase alkB homolog 5 |
| 2 | A | PYRIDINE-2,4-DICARBOXYLIC ACID | non-polymer | 167.1 | 1 | Chemie (PD2) | |||
| 3 | A | MANGANESE (II) ION | non-polymer | 54.9 | 1 | Chemie (MN) | |||
| 4 | water | water | 18.0 | 4 | Chemie (HOH) |
Sequence modifications
A: 66 - 292 (UniProt: Q6P6C2)
| PDB | External Database | Details |
|---|---|---|
| Gly 63 | - | expression tag |
| His 64 | - | expression tag |
| Met 65 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 26385.1 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 222.1 | |
| All* | Total formula weight | 26607.2 |
