4NR0
Crystal structure of the Pseudomonas aeruginosa Enoyl-Acyl Carrier Protein Reductase (FabI) in complex with NAD+ and triclosan
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Enoyl-[acyl-carrier-protein] reductase [NADH] FabI | polymer | 273 | 29106.9 | 4 | UniProt (Q9ZFE4) Pfam (PF13561) | Pseudomonas aeruginosa | ENR, NADH-dependent enoyl-ACP reductase |
| 2 | E, G, I, K (A, B, C, D) | NICOTINAMIDE-ADENINE-DINUCLEOTIDE | non-polymer | 663.4 | 4 | Chemie (NAD) | |||
| 3 | F, H, J, L (A, B, C, D) | TRICLOSAN | non-polymer | 289.5 | 4 | Chemie (TCL) | |||
| 4 | M, N, O, P (A, B, C, D) | water | water | 18.0 | 807 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 265 (UniProt: Q9ZFE4)
| PDB | External Database | Details |
|---|---|---|
| Leu 266 | - | expression tag |
| Glu 267 | - | expression tag |
| His 268 | - | expression tag |
| His 269 | - | expression tag |
| His 270 | - | expression tag |
| His 271 | - | expression tag |
| His 272 | - | expression tag |
| His 273 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 116427.7 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 3811.9 | |
| All* | Total formula weight | 120239.6 |
