4NR0

Crystal structure of the Pseudomonas aeruginosa Enoyl-Acyl Carrier Protein Reductase (FabI) in complex with NAD+ and triclosan

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D	Enoyl-[acyl-carrier-protein] reductase [NADH] FabI	polymer	273	29106.9	4	UniProt (Q9ZFE4) Pfam (PF13561) In PDB	Pseudomonas aeruginosa	ENR, NADH-dependent enoyl-ACP reductase
2	A, B, C, D	NICOTINAMIDE-ADENINE-DINUCLEOTIDE	non-polymer		663.4	4	Chemie (NAD)
3	A, B, C, D	TRICLOSAN	non-polymer		289.5	4	Chemie (TCL)
4		water	water		18.0	807	Chemie (HOH)

Sequence modifications

A, B, C, D: 1 - 265 (UniProt: Q9ZFE4)

PDB	External Database	Details
Leu 266	-	expression tag
Glu 267	-	expression tag
His 268	-	expression tag
His 269	-	expression tag
His 270	-	expression tag
His 271	-	expression tag
His 272	-	expression tag
His 273	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	116427.7
Non-Polymers*	Number of molecules	8
	Total formula weight	3811.9
All*	Total formula weight	120239.6

*Water molecules are not included.