4NPU

Crystal Structure of HIV-1 Protease Multiple Mutant P51

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Protease	polymer	99	10784.6	2	UniProt (O38896) Pfam (PF00077)	Human immunodeficiency virus 1
2	C, D (A, B)	water	water		18.0	134	Chemie (HOH)

Sequence modifications

A, B: 1 - 99 (UniProt: O38896)

PDB	External Database	Details
Lys 7	Gln 7	engineered mutation
Asn 25	Asp 25	engineered mutation
Ile 32	Val 32	engineered mutation
Phe 33	Leu 33	engineered mutation
Ser 37	Asn 37	engineered mutation
Met 54	Val 54	engineered mutation
Ala 67	Cys 67	engineered mutation
Ile 82	Ala 82	engineered mutation
Val 84	Ile 84	engineered mutation
Ala 95	Cys 95	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	21569.3
All*	Total formula weight	21569.3

*Water molecules are not included.