4NP7
Structure of phosphotriesterase mutant (S308L/Y309A) from Agrobacterium radiobacter with diethyl thiophosphate bound in the active site
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Phosphotriesterase | polymer | 329 | 35608.6 | 1 | UniProt (Q93LD7) Pfam (PF02126) In PDB | Agrobacterium tumefaciens | |
| 2 | A | FE (II) ION | non-polymer | 55.8 | 1 | Chemie (FE2) | |||
| 3 | A | COBALT (II) ION | non-polymer | 58.9 | 1 | Chemie (CO) | |||
| 4 | A | O,O-DIETHYL HYDROGEN THIOPHOSPHATE | non-polymer | 170.2 | 1 | Chemie (DPJ) | |||
| 5 | A | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 6 | water | water | 18.0 | 159 | Chemie (HOH) |
Sequence modifications
A: 33 - 361 (UniProt: Q93LD7)
| PDB | External Database | Details |
|---|---|---|
| Ala 92 | Ser 91 | conflict |
| Asp 265 | Asn 264 | conflict |
| Leu 308 | Ser 307 | engineered mutation |
| Ala 309 | Tyr 308 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 35608.6 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 347.0 | |
| All* | Total formula weight | 35955.6 |
