4NP3
Crystal structure of the murine cd44 hyaluronan binding domain complex with a small molecule
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | CD44 antigen | polymer | 150 | 16724.6 | 1 | UniProt (P15379) Pfam (PF00193) | Mus musculus (mouse) | Extracellular matrix receptor III, ECMR-III, GP90 lymphocyte homing/adhesion receptor, HUTCH-I, Hermes antigen, Hyaluronate receptor, Lymphocyte antigen 24, Ly-24, Phagocytic glycoprotein 1, PGP-1, Phagocytic glycoprotein I, PGP-I |
| 2 | B (A) | 2-[(4-methyl-1H-imidazol-5-yl)methyl]-1,2,3,4-tetrahydroisoquinolin-8-amine | non-polymer | 242.3 | 1 | Chemie (2L2) | |||
| 3 | C (A) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 1 | Chemie (DMS) | |||
| 4 | D (A) | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID | non-polymer | 195.2 | 1 | Chemie (MES) | |||
| 5 | E, F, G (A) | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 6 | H (A) | water | water | 18.0 | 116 | Chemie (HOH) |
Sequence modifications
A: 25 - 173 (UniProt: P15379)
| PDB | External Database | Details |
|---|---|---|
| Asn 24 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 16724.6 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 803.9 | |
| All* | Total formula weight | 17528.5 |
