4NOL

Crystal structure of proenzyme asparaginyl endopeptidase (AEP)/Legumain mutant D233A at pH 7.5

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Legumain	polymer	441	50222.8	2	UniProt (O89017) Pfam (PF01650) Pfam (PF20985) In PDB	Mus musculus (mouse)	Asparaginyl endopeptidase, Protease, cysteine 1
2		water	water		18.0	83	Chemie (HOH)

Sequence modifications

A, B: 1 - 435 (UniProt: O89017)

PDB	External Database	Details
Ala 233	Asp 233	engineered mutation
His 436	-	EXPRESSION TAG
His 437	-	EXPRESSION TAG
His 438	-	EXPRESSION TAG
His 439	-	EXPRESSION TAG
His 440	-	EXPRESSION TAG
His 441	-	EXPRESSION TAG

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	100445.5
All*	Total formula weight	100445.5

*Water molecules are not included.