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4NLZ

Structure of human DNA polymerase beta complexed with nicked DNA containing a mismatched template 8BrG and incoming GTP

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
DNA polymerase betapolymer32937536.81UniProt (P06746)
Pfam (PF14716)
Pfam (PF10391)
Pfam (PF14792)
Pfam (PF14791)
Homo sapiens (human)
2B
(T)
5'-D(*CP*CP*GP*AP*CP*(BGM)P*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'polymer164923.01
3C
(P)
5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*AP*G)-3'polymer113414.21
4D
(D)
5'-D(P*GP*TP*CP*GP*G)-3'polymer51536.01
5E
(A)
MAGNESIUM IONnon-polymer24.31Chemie (MG)
6F, H
(A, D)
SODIUM IONnon-polymer23.02Chemie (NA)
7G
(A)
PHOSPHATE IONnon-polymer95.01Chemie (PO4)
8I, J, K, L
(A, T, P, D)
waterwater18.057Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight47410.1
Non-Polymers*Number of molecules4
Total formula weight165.3
All*Total formula weight47575.3
*Water molecules are not included.

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PDB entries from 2025-06-11

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