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4NLK

Structure of human DNA polymerase beta complexed with 8BrG in the template base-paired with incoming non-hydrolyzable CTP

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(T)
5'-D(*CP*CP*GP*AP*CP*(BGM)P*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'polymer164923.01
2B
(P)
5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3'polymer103085.01
3C
(D)
5'-D(P*GP*TP*CP*GP*G)-3'polymer51536.01
4D
(A)
DNA polymerase betapolymer32937536.81UniProt (P06746)
Pfam (PF14716)
Pfam (PF10391)
Pfam (PF14792)
Pfam (PF14791)
Homo sapiens (human)
5E, F
(A)
MAGNESIUM IONnon-polymer24.32Chemie (MG)
6G, H
(A)
SODIUM IONnon-polymer23.02Chemie (NA)
7I
(A)
2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidinenon-polymer466.21Chemie (0KX)
8J, K, L
(T, P, A)
waterwater18.066Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight47080.9
Non-Polymers*Number of molecules5
Total formula weight560.8
All*Total formula weight47641.6
*Water molecules are not included.

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PDB entries from 2025-06-11

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