4NL5

Mycobacterium tuberculosis heme-degrading protein MhuD in complex with heme and cyanide

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Heme-degrading monooxygenase HmoB	polymer	123	13192.9	2	UniProt (O06156) Pfam (PF03992) UniProt (by SIFTS) (P9WKH3)	Mycobacterium tuberculosis	Heme oxygenase, Mycobacterial heme utilization degrader, MHUD
2	C, F (A, B)	PROTOPORPHYRIN IX CONTAINING FE	non-polymer		616.5	2	Chemie (HEM)
3	D, G (A, B)	CYANIDE ION	non-polymer		26.0	2	Chemie (CYN)
4	E, H (A, B)	ACETATE ION	non-polymer		59.0	2	Chemie (ACT)
5	I, J (A, B)	water	water		18.0	94	Chemie (HOH)

Sequence modifications

A, B: 1 - 105 (UniProt: O06156)

PDB	External Database	Details
Gly 106	-	expression tag
Val 107	-	expression tag
Pro 108	-	expression tag
Arg 109	-	expression tag
Gly 110	-	expression tag
Lys 111	-	expression tag
Leu 112	-	expression tag
Ala 113	-	expression tag
Ala 114	-	expression tag
Ala 115	-	expression tag
Leu 116	-	expression tag
Glu 117	-	expression tag
His 118	-	expression tag
His 119	-	expression tag
His 120	-	expression tag
His 121	-	expression tag
His 122	-	expression tag
His 123	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	26385.8
Non-Polymers*	Number of molecules	6
	Total formula weight	1403.1
All*	Total formula weight	27788.9

*Water molecules are not included.