4NKG

Crystal structure of SspH1 LRR domain in complex PKN1 HR1b domain

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C	E3 ubiquitin-protein ligase sspH1	polymer	246	26580.1	2	UniProt (D0ZVG2) Pfam (PF00560) In PDB	Salmonella enterica subsp. enterica serovar Typhimurium	Salmonella secreted protein H1, Secreted effector protein sspH1
2	B, D	Serine/threonine-protein kinase N1	polymer	82	9066.5	2	UniProt (Q16512) Pfam (PF02185) In PDB	Homo sapiens (human)	Protease-activated kinase 1, PAK-1, Protein kinase C-like 1, Protein kinase C-like PKN, Protein kinase PKN-alpha, Protein-kinase C-related kinase 1, Serine-threonine protein kinase N
3	A, C	HEXANE-1,6-DIOL	non-polymer		118.2	2	Chemie (HEZ)
4		water	water		18.0	3	Chemie (HOH)

Sequence modifications

A, C: 161 - 405 (UniProt: D0ZVG2)

PDB	External Database	Details
Gly 160	-	expression tag

B, D: 122 - 199 (UniProt: Q16512)

PDB	External Database	Details
Gly 118	-	expression tag
Ala 119	-	expression tag
Met 120	-	expression tag
Asp 121	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	71293.1
Non-Polymers*	Number of molecules	2
	Total formula weight	236.3
All*	Total formula weight	71529.4

*Water molecules are not included.