4NJD
Structure of p21-activated kinase 4 with a novel inhibitor KY-04031
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Serine/threonine-protein kinase PAK 4 | polymer | 296 | 33424.8 | 1 | UniProt (O96013) Pfam (PF00069) | Homo sapiens (human) | p21-activated kinase 4, PAK-4 |
| 2 | B (A) | N-(1H-indazol-5-yl)-N'-[2-(1H-indol-3-yl)ethyl]-6-methoxy-1,3,5-triazine-2,4-diamine | non-polymer | 400.4 | 1 | Chemie (NJD) | |||
| 3 | C (A) | water | water | 18.0 | 43 | Chemie (HOH) |
Sequence modifications
A: 300 - 591 (UniProt: O96013)
| PDB | External Database | Details |
|---|---|---|
| Gly 296 | - | expression tag |
| Ser 297 | - | expression tag |
| His 298 | - | expression tag |
| Met 299 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 33424.8 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 400.4 | |
| All* | Total formula weight | 33825.3 |
