4NID
Crystal structure of AlkB protein with cofactors bound to dsDNA containing m6A
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Alpha-ketoglutarate-dependent dioxygenase AlkB | polymer | 205 | 22830.1 | 1 | UniProt (P05050) | Escherichia coli | Alkylated DNA repair protein AlkB, DNA oxidative demethylase AlkB |
| 2 | B (B) | 5'-D(*TP*AP*GP*GP*TP*AP*AP*(6MA)P*AP*CP*CP*GP*T)-3' | polymer | 13 | 4073.8 | 1 | |||
| 3 | C (C) | 5'-D(*AP*AP*CP*GP*GP*TP*AP*TP*TP*AP*CP*CP*T)-3' | polymer | 13 | 3950.6 | 1 | |||
| 4 | D (A) | MANGANESE (II) ION | non-polymer | 54.9 | 1 | Chemie (MN) | |||
| 5 | E (A) | 2-OXOGLUTARIC ACID | non-polymer | 146.1 | 1 | Chemie (AKG) | |||
| 6 | F, G, H (A, B, C) | water | water | 18.0 | 333 | Chemie (HOH) |
Sequence modifications
A: 12 - 216 (UniProt: P05050)
| PDB | External Database | Details |
|---|---|---|
| Cys 129 | Ser 129 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 30854.5 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 201.0 | |
| All* | Total formula weight | 31055.5 |
