4NHM
Crystal structure of Tpa1p from Saccharomyces cerevisiae, termination and polyadenylation protein 1, in complex with N-[(1-chloro-4-hydroxyisoquinolin-3-yl)carbonyl]glycine (IOX3/UN9)
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | PKHD-type hydroxylase TPA1 | polymer | 647 | 74494.5 | 1 | UniProt (P40032) Pfam (PF10637) In PDB | Saccharomyces cerevisiae (Baker's yeast) | Termination and polyadenylation protein 1 |
2 | A | N-[(1-CHLORO-4-HYDROXYISOQUINOLIN-3-YL)CARBONYL]GLYCINE | non-polymer | 280.7 | 1 | Chemie (UN9) | |||
3 | A | MANGANESE (II) ION | non-polymer | 54.9 | 1 | Chemie (MN) | |||
4 | A | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
5 | water | water | 18.0 | 535 | Chemie (HOH) |
Sequence modifications
A: 21 - 644 (UniProt: P40032)
PDB | External Database | Details |
---|---|---|
Met -2 | - | expression tag |
His -1 | - | expression tag |
His 0 | - | expression tag |
His 1 | - | expression tag |
His 2 | - | expression tag |
His 3 | - | expression tag |
His 4 | - | expression tag |
Ser 5 | - | expression tag |
Ser 6 | - | expression tag |
Gly 7 | - | expression tag |
Val 8 | - | expression tag |
Asp 9 | - | expression tag |
Leu 10 | - | expression tag |
Gly 11 | - | expression tag |
Thr 12 | - | expression tag |
Glu 13 | - | expression tag |
Asn 14 | - | expression tag |
Leu 15 | - | expression tag |
Tyr 16 | - | expression tag |
Phe 17 | - | expression tag |
Gln 18 | - | expression tag |
Ser 19 | - | expression tag |
Met 20 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 74494.5 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 519.8 | |
All* | Total formula weight | 75014.3 |