4NDY

Human MHF1-MHF2 DNA complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	E, O	DNA (26-MER)	polymer	26	8098.4	2		Synthetic DNA
2	F, P	DNA (26-MER)	polymer	26	7864.1	2		Synthetic DNA
3	C, G, A, I, J...	Centromere protein S	polymer	105	12091.9	10	UniProt (Q8N2Z9) Pfam (PF15630) In PDB	Homo sapiens (human)	CENP-S, Apoptosis-inducing TAF9-like domain-containing protein 1, FANCM-interacting histone fold protein 1, Fanconi anemia-associated polypeptide of 16 kDa
4	D, H, B, L, M...	Centromere protein X	polymer	74	8398.8	10	UniProt (A8MT69) Pfam (PF09415) In PDB	Homo sapiens (human)	CENP-X, FANCM-interacting histone fold protein 2, Fanconi anemia-associated polypeptide of 10 kDa, Retinoic acid-inducible gene D9 protein homolog, Stimulated by retinoic acid gene 13 protein homolog

Sequence modifications

C, G, A, I, J, K, Q, R, S, T: 14 - 105 (UniProt: Q8N2Z9)

PDB	External Database	Details
Ala 39	Glu 39	conflict
Ala 106	-	expression tag
Asn 107	-	expression tag
Leu 108	-	expression tag
Glu 109	-	expression tag
Arg 110	-	expression tag
Lys 111	-	expression tag
Ala 112	-	expression tag
Gln 113	-	expression tag
Lys 114	-	expression tag
Lys 115	-	expression tag
Lys 116	-	expression tag
Lys 117	-	expression tag
Ser 118	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	24
	Total formula weight	236832.4
All*	Total formula weight	236832.4

*Water molecules are not included.