4NDG
Human Aprataxin (Aptx) bound to RNA-DNA and Zn - adenosine vanadate transition state mimic complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Aprataxin | polymer | 182 | 21259.8 | 2 | UniProt (Q7Z2E3) Pfam (PF11969) Pfam (PF16278) In PDB | Homo sapiens (human) | Forkhead-associated domain histidine triad-like protein, FHA-HIT |
| 2 | D, G | 5'-R(P*G)-D(P*TP*TP*AP*TP*GP*AP*TP*TP*C)-3' | polymer | 10 | 3066.0 | 2 | |||
| 3 | E, H | 5'-D(*GP*AP*AP*TP*CP*AP*TP*AP*AP*C)-3' | polymer | 10 | 3037.0 | 2 | |||
| 4 | A, B | adenosine-5'-vanadate | non-polymer | 350.2 | 2 | Chemie (V5A) | |||
| 5 | A, B | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 6 | water | water | 18.0 | 25 | Chemie (HOH) |
Sequence modifications
A, B: 165 - 342 (UniProt: Q7Z2E3)
| PDB | External Database | Details |
|---|---|---|
| Gly 161 | - | expression tag |
| Ser 162 | - | expression tag |
| His 163 | - | expression tag |
| Met 164 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 54725.6 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 831.2 | |
| All* | Total formula weight | 55556.8 |
