4NDG

Human Aprataxin (Aptx) bound to RNA-DNA and Zn - adenosine vanadate transition state mimic complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Aprataxin	polymer	182	21259.8	2	UniProt (Q7Z2E3) Pfam (PF11969) Pfam (PF16278)	Homo sapiens (human)	Forkhead-associated domain histidine triad-like protein, FHA-HIT
2	C, E (D, G)	5'-R(P*G)-D(P*TP*TP*AP*TP*GP*AP*TP*TP*C)-3'	polymer	10	3066.0	2
3	D, F (E, H)	5'-D(*GP*AP*AP*TP*CP*AP*TP*AP*AP*C)-3'	polymer	10	3037.0	2
4	G, I (A, B)	adenosine-5'-vanadate	non-polymer		350.2	2	Chemie (V5A)
5	H, J (A, B)	ZINC ION	non-polymer		65.4	2	Chemie (ZN)
6	K, L, M, N, O... (A, B, D, E, G...)	water	water		18.0	25	Chemie (HOH)

Sequence modifications

A, B: 165 - 342 (UniProt: Q7Z2E3)

PDB	External Database	Details
Gly 161	-	expression tag
Ser 162	-	expression tag
His 163	-	expression tag
Met 164	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	54725.6
Non-Polymers*	Number of molecules	4
	Total formula weight	831.2
All*	Total formula weight	55556.8

*Water molecules are not included.