4NAQ

Crystal structure of porcine aminopeptidase-N complexed with poly-alanine

Replaces:  4HOLReplaces:  4FKF

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Aminopeptidase N	polymer	907	103392.0	1	UniProt (P15145) Pfam (PF17900) Pfam (PF01433) Pfam (PF11838)	Sus scrofa (pig)	AP-N, pAPN, Alanyl aminopeptidase, Aminopeptidase M, AP-M, Microsomal aminopeptidase, gp130
2	B (B)	poly A peptide	polymer	7	515.6	1
3	C, D, E, F, G (C, D, E, F, G)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	5	In PDB GlyTouCan (G42666HT)
4	H, I, J, K, L (A)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	5	Chemie (NAG)
5	M, N, O, P, Q... (A)	SULFATE ION	non-polymer		96.1	11	Chemie (SO4)
6	X (A)	ZINC ION	non-polymer		65.4	1	Chemie (ZN)
7	Y, Z (A, B)	water	water		18.0	788	Chemie (HOH)

Sequence modifications

A: 64 - 963 (UniProt: P15145)

PDB	External Database	Details
Phe 107	Leu 107	conflict
Gln 384	Glu 384	conflict
Ser 964	-	expression tag
His 965	-	expression tag
His 966	-	expression tag
His 967	-	expression tag
His 968	-	expression tag
His 969	-	expression tag
His 970	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	103907.6
Branched	Number of molecules	5
	Total formula weight	2122.0
Non-Polymers*	Number of molecules	17
	Total formula weight	2228.1
All*	Total formula weight	108257.8

*Water molecules are not included.