4NA9
Factor VIIa in complex with the inhibitor 3'-amino-5'-[(2s,4r)-6-carbamimidoyl-4-phenyl-1,2,3,4-tetrahydroquinolin-2-yl]biphenyl-2-carboxylic acid
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | H | Coagulation factor VII heavy chain | polymer | 254 | 28103.3 | 1 | UniProt (P08709) Pfam (PF00089) In PDB | Homo sapiens (human) | Proconvertin, Serum prothrombin conversion accelerator, SPCA |
2 | L | Coagulation factor VII light chain | polymer | 55 | 6030.8 | 1 | UniProt (P08709) Pfam (PF14670) In PDB | Homo sapiens (human) | Proconvertin, Serum prothrombin conversion accelerator, SPCA |
3 | H | 3'-amino-5'-[(2S,4R)-6-carbamimidoyl-4-phenyl-1,2,3,4-tetrahydroquinolin-2-yl]biphenyl-2-carboxylic acid | non-polymer | 462.5 | 1 | Chemie (1T7) | |||
4 | H | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
5 | water | water | 18.0 | 177 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 34134.1 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 502.6 | |
All* | Total formula weight | 34636.7 |