4N90
Crystal structure of ternary complex of TRAIL, DR5, and Fab fragment from a DR5 agonist antibody
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (R, S, T) | Tumor necrosis factor receptor superfamily member 10B | polymer | 126 | 14193.9 | 3 | UniProt (O14763) Pfam (PF00020) | Homo sapiens (human) | Death receptor 5, TNF-related apoptosis-inducing ligand receptor 2, TRAIL receptor 2, TRAIL-R2 |
| 2 | D, E, F (A, B, C) | Tumor necrosis factor ligand superfamily member 10 | polymer | 168 | 19520.9 | 3 | UniProt (P50591) Pfam (PF00229) | Homo sapiens (human) | Apo-2 ligand, Apo-2L, TNF-related apoptosis-inducing ligand, Protein TRAIL |
| 3 | G, I, K (E, G, I) | Fab light chain | polymer | 215 | 23415.0 | 3 | Homo sapiens | ||
| 4 | H, J, L (D, F, H) | Fab heavy chain | polymer | 224 | 23774.6 | 3 | Homo sapiens | ||
| 5 | M (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 242712.6 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 65.4 | |
| All* | Total formula weight | 242778.1 |
